Clik here to view.
After $14B exit, Karuna co-founder finds next bet; Ex-Regenxbio CEO Ken Mills...
Andrew Miller Andrew Miller has quickly made his first move after the technology he invented, KarXT, secured an FDA approval last week. The regulator’s nod for Bristol Myers Squibb’s Cobenfy (KarXT)...
View ArticleSanofi sells rare disease drug Enjaymo to Recordati for $825M upfront
Sanofi is offloading its rare autoimmune disease medicine Enjaymo to an Italian pharmaceutical company for $825 million upfront. Recordati, based in Milan, said Friday it will pay up to an additional...
View ArticleBiotech's third quarter was relatively bright — with a few caveats
The weather is getting cooler, but biotech’s recovery is heating up. After a years-long wait-and-see game exhausted many industry insiders, recent signals indicate a mostly promising direction for drug...
View ArticleEditas sells future CRISPR license fees; Plus, news about Oncolytics Biotech
Editas sells future CRISPR licensing fees from Vertex: DRI Healthcare Trust is paying $57 million upfront to the gene editing company in exchange for future licensing payments from Vertex, which struck...
View ArticleJ&J discontinues mid-stage dengue study, citing deprioritization of...
What’s left of Johnson & Johnson’s infectious disease work continues to shrink, after the company announced Friday that it had stopped work on a mid-stage study of its dengue virus antiviral. The...
View ArticleAlnylam agrees to drop patent lawsuit against Moderna over Covid-19 vaccine
Alnylam Pharmaceuticals has agreed to drop its 2023 patent lawsuit against Moderna in a Delaware court following a judge’s ruling in September. In an Oct. 2 filing, Alnylam said the ruling “precludes...
View ArticleRSV vaccines off to a sluggish start in US this season, with volumes behind 2023
This season’s uptake of RSV vaccines in the US has been slower than expected, according to Wall Street analysts tracking prescriptions, and appears to be missing even modest projections for growth...
View ArticleEMA reviews hair loss products following concerns about suicidal thoughts
The European Medicines Agency is looking more closely at medicines used to treat hair loss and a condition caused by an enlarged prostate over concerns about suicidal thoughts. The review encompasses...
View ArticleBARDA doles out $72M to Sanofi, GSK and CSL for bird flu vaccine supply
The Center for Biomedical Advanced Research and Development Authority (BARDA) is giving $72 million to three drugmakers to help fortify the US supply of bird flu vaccine ahead of 2025. The funding was...
View ArticleWuXi companies consider sale of units impacted by Biosecure; J&J, Bayer trim...
Welcome back to Endpoints Weekly, your review of the week’s top biopharma headlines. Want this in your inbox every Saturday morning? Current Endpoints readers can visit their reader profile to add...
View ArticleMany drug price proposals from candidates and Congress won't have much...
Want to lower drug prices? Good luck. In a new report released Friday, the nonpartisan Congressional Budget Office (CBO) detailed how many of the campaign proposals mentioned by presidential nominees...
View ArticleNovo and Viatris settle Ozempic patent suit as generic entry date remains...
Novo Nordisk and Mylan Pharmaceuticals, now part of Viatris, have settled their patent dispute over Novo’s blockbuster diabetes drug Ozempic. The Danish company declined to comment on the terms of its...
View ArticleJ&J’s ‘pretzel’ drug-device therapy fails Phase 3 in certain bladder cancer...
Johnson & Johnson’s drug-device combo has disappointed in a late-stage test in people with an advanced form of bladder cancer, but it says it is still confident in the technology’s overall...
View ArticleClik here to view.
Exclusive: Tiny startup with big vision to extend healthspan by 20 years says...
Last August, stem cell biologist and bit.bio founder Mark Kotter launched a new startup with an ambitious goal: within a year, to identify every gene that plays a role in restoring or repairing aging...
View ArticleMerck partners with small UK biotech to drug fibroblasts for fibrosis, I&I...
As Merck builds out its immunology research lab in London, it’s partnering with a local biotech startup that has remained relatively quiet since its seed round in 2021. The pharma giant said Tuesday...
View ArticleClik here to view.
Astellas places new bet on gene therapy in $50M upfront deal with London's...
As it works to rebuild from an earlier gene therapy setback, Astellas is doubling down on the one-and-done modality in a new deal with a London-based startup already in the clinic. Astellas said...
View ArticleClik here to view.
Sage faces third Phase 2 fail in six months as dalzanemdor misses goal in...
Sage Therapeutics is reeling from another mid-stage setback as its investigational medicine dalzanemdor has missed the mark in a Phase 2 mild cognitive impairment trial. The drug, an NMDA receptor...
View ArticleClik here to view.
Exclusive: Lilly backs a16z-funded Arda Therapeutics' $43M Series A to take...
A three-year-old startup based on decades of research in cell depletion is betting that some of the hottest tools in oncology may work even better in other diseases. Arda Therapeutics has raised a $43...
View ArticleOrasis snags $78M to launch presbyopia eye drops more than a year after FDA...
Last October was an FDA approval. This October is a $68 million fundraising round. Next year, maybe a drug launch. Orasis Pharmaceuticals announced a Series D round on Tuesday, plus another $10 million...
View ArticleClik here to view.
Biogen to seek approval for high-dose Spinraza after unveiling new data
Nearly eight years after securing a historic first approval for a spinal muscular atrophy drug, Biogen is seeking to launch a new dosing regimen of Spinraza. Clinical trial data unveiled on Tuesday...
View Article